Hypercalcemia-induced ST-segment elevation mimicking acute myocardial infarction

Shawn P E Nishi1, Nestor A Barbagelata, Shaul Atar

  • 1Division of Cardiology, Department of Internal Medicine, University of Texas Medical Branch, Galveston 77555-0553, USA.

Insights

Severe hypercalcemia can mimic a heart attack by causing ST elevation. Prompt correction of high calcium levels resolved the ST elevation, highlighting a rare but critical diagnosis.

Area of Science:

  • Cardiology
  • Endocrinology
  • Internal Medicine

Background:

  • Acute myocardial infarction (AMI) is a common emergency diagnosis characterized by ST elevation on electrocardiogram (ECG).
  • Differential diagnoses for ST elevation include pericarditis, early repolarization, and hypercalcemia.

Observation:

  • A patient presented with chest pain and ST elevation, initially suspected as AMI.
  • Coronary angiography showed normal arteries and serum troponin levels were not elevated.

Findings:

  • The patient was diagnosed with severe hypercalcemia.
  • ST segment elevation resolved completely following correction of hypercalcemia.

Implications:

  • This case highlights hypercalcemia as a rare cause of ST elevation mimicking acute myocardial infarction.
  • Recognition of this association is crucial for accurate diagnosis and timely management, avoiding unnecessary invasive procedures.

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