Hypercalcemia-induced ST-segment elevation mimicking acute myocardial infarction
Shawn P E Nishi1, Nestor A Barbagelata, Shaul Atar
1Division of Cardiology, Department of Internal Medicine, University of Texas Medical Branch, Galveston 77555-0553, USA.
Insights
Severe hypercalcemia can mimic a heart attack by causing ST elevation. Prompt correction of high calcium levels resolved the ST elevation, highlighting a rare but critical diagnosis.
Area of Science:
- Cardiology
- Endocrinology
- Internal Medicine
Background:
- Acute myocardial infarction (AMI) is a common emergency diagnosis characterized by ST elevation on electrocardiogram (ECG).
- Differential diagnoses for ST elevation include pericarditis, early repolarization, and hypercalcemia.
Observation:
- A patient presented with chest pain and ST elevation, initially suspected as AMI.
- Coronary angiography showed normal arteries and serum troponin levels were not elevated.
Findings:
- The patient was diagnosed with severe hypercalcemia.
- ST segment elevation resolved completely following correction of hypercalcemia.
Implications:
- This case highlights hypercalcemia as a rare cause of ST elevation mimicking acute myocardial infarction.
- Recognition of this association is crucial for accurate diagnosis and timely management, avoiding unnecessary invasive procedures.
Abstract:
We describe a patient who presented with abdominal pain radiating to the chest and ST elevation in the precordial leads, mimicking acute myocardial infarction. Urgent coronary angiography revealed normal coronary arteries and his serum troponin has not increased. Subsequently, he was found to have severe hypercalcemia. ST segment elevation resolved after correction of hypercalcemia. This phenomenon of ST elevation secondary to hypercalcemia has been described only two times in the English literature to date.
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