Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Thyroid medications during pregnancy.

Thien-Giang Bach-Huynh1, Jacqueline Jonklaas

  • 1Division of Endocrinology and Metabolism, Georgetown University, Suite 232, Bldg. D, 4000 Reservoir Road, NW, Washington, DC 20007, USA.

Therapeutic Drug Monitoring
|June 17, 2006
PubMed
Summary

Thyroid hormone levels change significantly during pregnancy. Using non-pregnant reference ranges can lead to misdiagnosis; trimester-specific intervals are essential for accurate thyroid function assessment.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reply to 'Post-thyrotoxicosis weight gain: time to stratify and treat?'

Nature reviews. Endocrinology·2026
Same author

Radioactive Iodine Symptom Burden, Psychosocial Factors, and Health-related Quality of Life among Differentiated Thyroid Cancer Survivors: A Cross-Sectional Analysis.

Journal of psychosocial oncology research and practice·2026
Same author

The Influence of Thyroid Dysfunction on Body Composition and Weight Trajectory.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·2025
Same author

Patient Perspectives Toward a Decision Aid for Radioactive Iodine Treatment for Intermediate Risk Thyroid Cancer.

International journal of behavioral medicine·2025
Same author

The complexity of the relationship between thyroid disease and body weight.

Nature reviews. Endocrinology·2025
Same author

Safe Optimization of Thyroid Hormone Therapy.

The Journal of clinical endocrinology and metabolism·2025

Area of Science:

  • Obstetrics and Gynecology
  • Endocrinology
  • Reproductive Medicine

Background:

  • Thyroid physiology undergoes significant adaptations during pregnancy to support placental and fetal development.
  • Non-pregnant reference intervals for thyroid parameters are inadequate for assessing thyroid status in pregnant women.
  • Accurate diagnosis and management of thyroid dysfunction in pregnancy necessitate trimester-specific reference intervals.

Purpose of the Study:

  • To emphasize the critical need for trimester-specific thyroid function reference intervals in pregnant women.
  • To highlight the importance of appropriate diagnosis and management of thyroid dysfunction during pregnancy.
  • To provide guidance on the treatment of hypothyroidism and hyperthyroidism in pregnant individuals.

Main Methods:

Related Experiment Videos

  • Review of physiological changes in thyroid parameters during euthyroid pregnancy.
  • Discussion of diagnostic criteria for hypothyroidism and hyperthyroidism using pregnancy-specific reference intervals.
  • Overview of therapeutic strategies for thyroid dysfunction in pregnancy, including levothyroxine, thionamides, and surgical options.

Main Results:

  • Euthyroid pregnancy involves dramatic physiological thyroid changes, necessitating trimester-specific reference intervals.
  • Hypothyroidism and hyperthyroidism require diagnosis with appropriate pregnancy intervals and timely, specific treatments.
  • Levothyroxine is recommended for hypothyroidism, while thionamides are primary for hyperthyroidism, with close monitoring to prevent maternal and fetal complications.

Conclusions:

  • Trimester-specific reference intervals are crucial for accurate thyroid status assessment in pregnancy.
  • Appropriate management of maternal thyroid dysfunction, including hypothyroidism and hyperthyroidism, is vital for both maternal and fetal well-being.
  • Iodine sufficiency through supplementation is recommended, and radioiodine therapy is contraindicated during pregnancy.