Antithrombotic therapy for percutaneous coronary intervention

This article outlines the antiplatelet and antithrombotic therapy used in contemporary percutaneous coronary interventions. It is a comprehensive review of past and present pharmacologic agents and includes a discussion of the more promising potential future therapies. The clinical trials that provide the basis for the current standard of care are provided, as are ongoing trials that will likely shape the future standard. This article is not intended to provide a detailed discussion of precise mechanistic or structural features of each agent but to serve as a practical clinical guide to the interventionalist when choosing specific pharmacotherapies for specific patients in the catheterization laboratory.