Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Liquid injectable silicone for soft tissue augmentation.

Chad L Prather1, Derek H Jones

  • 1Department of Dermatology, Louisiana State University Health Sciences Center School of Medicine, New Orleans, 70116, USA. cprath@lsuhsc.edu

Dermatologic Therapy
|June 21, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nonhealing Ulcer on the Lower Lip.

Cutis·2025
Same author

How dermatologic surgeons decide to proceed with surgery for nonmelanoma skin cancer when site identification is initially uncertain: A nationwide, multicenter, prospective study.

Journal of the American Academy of Dermatology·2024
Same author

Neuromodulators in Men.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]·2024
Same author

A Multicenter, Randomized, Evaluator-Blinded Study to Examine the Safety and Effectiveness of Hyaluronic Acid Filler in the Correction of Infraorbital Hollows.

Aesthetic surgery journal·2024
Same author

Outcomes of cutaneous surgery for nonmelanoma skin cancer in patients with different Fitzpatrick skin types: A nationwide, multicenter, prospective study.

Journal of the American Academy of Dermatology·2024
Same author

PrabotulinumtoxinA for Treatment of Millennials With Moderate to Severe Glabellar Lines: Post Hoc Analyses of the Phase III Clinical Study Data.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]·2022
Same journal

Increased Risk of Cutaneous T-Cell Lymphoma Development after Dupilumab Use for Atopic Dermatitis.

Dermatologic therapy·2024
Same journal

Correction to "Adjuvant PD-1 inhibitor versus high-dose interferon α-2b for Chinese patients with cutaneous and acral melanoma: A retrospective cohort analysis".

Dermatologic therapy·2022
Same journal

A case of erythema nodosum concomitant with ulcerative colitis relieved by tofacitinib.

Dermatologic therapy·2022
Same journal

A case report of vitiligo following toripalimab therapy for a patient with metastatic melanoma.

Dermatologic therapy·2022
Same journal

High versus low dose oral isotretinoin in the treatment of cutaneous and genital warts.

Dermatologic therapy·2022
Same journal

Evaluation of the efficacy and relapse rates of treatment protocols for moderate acne using isotretinoin based on the global acne grading system: Randomized, controlled, comparative study.

Dermatologic therapy·2022
See all related articles

Modern purified liquid injectable silicone, when used with strict protocols, offers effective soft tissue augmentation for correcting scars and facial lipoatrophy with minimal complications. Its use is supported for long-term results in specific aesthetic and reconstructive applications.

Area of Science:

  • Dermatology
  • Plastic Surgery
  • Biomaterials Science

Background:

  • Liquid injectable silicone is a soft tissue filler with a history of complications, often linked to impurities.
  • Modern purified silicone products, approved by regulatory bodies, offer improved safety profiles.

Purpose of the Study:

  • To review the history and controversy surrounding silicone for soft tissue augmentation.
  • To describe current protocols, indications, and potential complications of using liquid injectable silicone.
  • To advocate for its continued investigation as a valuable treatment modality.

Main Methods:

  • Review of historical data and current literature on liquid injectable silicone.
  • Analysis of indications, patient selection criteria, and treatment protocols.

Related Experiment Videos

  • Discussion of safety measures and anticipated complications.

    • Main Results:

    • Historical complications were likely due to adulterants, not the silicone itself.
    • Approved purified silicone, when used correctly, can achieve effective soft tissue augmentation with minimal adverse events.
    • The agent is effective for long-term correction of scars and facial contour defects, including HIV-associated lipoatrophy.

    Conclusions:

    • Liquid injectable silicone remains a controversial yet important agent for soft tissue augmentation.
    • Strict adherence to protocols ensures safety and efficacy for correcting specific atrophies.
    • Further research is warranted to fully explore its therapeutic potential.