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Updated: Aug 7, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Congenital pathology of the pituitary gland and parasellar region
M Vittoria Spampinato1, Mauricio Castillo
1Department of Radiology, Medical University of South Carolina, Charleston, SC 29425, USA. spampin@musc.edu
Abstract:
The adenohypophysis and neurohypophysis originate from the combination of 2 events occurring during the fourth week of life, the development of Rathke pouch and of a neuroectodermal evagination of tissue from the floor of the diencephalon. Congenital pathology of the pituitary gland and parasellar regions derives from abnormalities of these coordinated events. In this article, we review the pathogenesis, clinical presentation, and imaging features of common and rare congenital disorders of the region of the sella turcica.
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