Related Experiment Video
Updated: Aug 7, 2026

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
A young man with nonhealing venous ulcers
M G Vloedbeld1, A W Venema, A J Smit
1Department of Internal Medicine, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands.
Buerger's disease caused nonhealing foot ulcers in a 35-year-old man. This condition resulted from combined venous and arterial insufficiency, highlighting the disease's complex vascular impact.
Area of Science:
- Vascular Medicine
- Dermatology
- Podiatry
Background:
- Buerger's disease is a rare inflammatory vascular condition affecting small and medium-sized arteries and veins, primarily in the legs and feet.
- It is strongly associated with tobacco use and can lead to critical limb ischemia.
Observation:
- A 35-year-old male presented with chronic, nonhealing ulcers on his left foot.
- The ulcer location was atypical, suggesting a complex underlying etiology beyond typical diabetic or pressure-related causes.
Findings:
- The patient exhibited signs of both venous insufficiency (secondary to deep venous thrombosis) and arterial insufficiency.
- Diagnostic evaluation confirmed Buerger's disease as the underlying cause of the patient's severe lower extremity vascular compromise.
Implications:
- This case underscores the importance of considering Buerger's disease in young patients with nonhealing lower extremity ulcers, even with atypical presentations.
- Accurate diagnosis and management of Buerger's disease are crucial to prevent limb loss and improve patient outcomes.
- The interplay of venous and arterial insufficiency in this case highlights the multifaceted nature of vascular compromise in Buerger's disease.
Related Concept Videos
Varicose Veins II: Diagnostic Studies and Interprofessional Care
Diabetic Foot Ulcer
Varicose Veins I: Introduction
Venous Thrombosis IV: Nursing Management
Venous Thrombosis III: Interprofessional Care
Peripheral Artery Disease V: Postoperative Nursing Management