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Integration of Bioinformatics Approaches and Experimental Validations to Understand the Role of Notch Signaling in Ovarian Cancer
Published on: January 12, 2020
Bioinformatics and cancer: an essential alliance
1Department of Bioinformatics, Centro de Investigación Príncipe Felipe, Valencia, Spain. jdopazo@cipf.es
Abstract:
Modern research in cancer has been revolutionized by the introduction of new high-throughput methodologies such as DNA microarrays. Keeping the pace with these technologies, the bioinformatics offer new solutions for data analysis and, what is more important, it permits to formulate a new class of hypothesis inspired in systems biology, more oriented to blocks of functionally-related genes. Although software implementations for this new methodologies is new there are some options already available. Bioinformatic solutions for other high-throughput techniques such as array-CGH of large-scale genotyping is also revised.
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