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Related Experiment Videos

Cochleovestibular dysfunction in ankylosing spondylitis.

Selim S Erbek1, H Seyra Erbek, Sema Yilmaz

  • 1Department of Otorhinolaryngology, Konya Teaching and Research Center, Baskent University, Konya, Turkey.

Audiology & Neuro-Otology
|June 23, 2006
PubMed
Summary

Ankylosing spondylitis (AS) is linked to cochleovestibular dysfunction, affecting hearing and balance. This study found significant differences in auditory function and balance system tests in AS patients compared to healthy individuals.

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Area of Science:

  • Rheumatology
  • Otolaryngology
  • Audiology
  • Neurology

Background:

  • Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease.
  • Inflammation in AS can potentially affect various organ systems beyond the musculoskeletal framework.
  • The impact of AS on cochlear and vestibular functions remains an area requiring further investigation.

Purpose of the Study:

  • To investigate cochlear and vestibular system functions in patients diagnosed with ankylosing spondylitis.
  • To compare auditory and balance system performance between AS patients and a healthy control group.
  • To identify potential associations between AS and specific types of cochleovestibular dysfunction.

Main Methods:

  • Recruited 32 patients with AS and 30 healthy controls.

Related Experiment Videos

  • Conducted comprehensive otolaryngologic examinations, including pure-tone audiometry, speech tests, and impedancemetry.
  • Utilized transient evoked otoacoustic emissions (TEOAE) for cochlear function assessment and electronystagmography (ENG) for vestibular function evaluation.
  • Main Results:

    • Patients with AS showed significantly reduced pure-tone averages at high frequencies (p < 0.05).
    • TEOAE reproducibility rates were significantly lower in AS patients (p = 0.03), with reduced signal-to-noise ratios at specific frequencies (p < 0.05).
    • Electronystagmography revealed pathologies in 34% of AS patients, including central (25%) and peripheral (9%) vestibular dysfunction.

    Conclusions:

    • This study demonstrates a significant association between ankylosing spondylitis and cochleovestibular dysfunction.
    • AS patients exhibit impaired auditory function and a higher prevalence of vestibular system abnormalities.
    • No correlation was observed between cochleovestibular dysfunction and clinical parameters such as age, disease duration, or medication in AS patients.