Tailored recombinant elastin-like polymers for advanced biomedical and nano(bio)technological applications
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Updated: Aug 7, 2026

Non-chromatographic Purification of Recombinant Elastin-like Polypeptides and their Fusions with Peptides and Proteins from Escherichia coli
Published on: June 9, 2014
F Javier Arias1, Virginia Reboto, Susana Martín
1BIOFORGE research group, Dpto. Física de la Materia Condensada, E.T.S.I.I., Universidad de Valladolid, Paseo del Cauce s/n, 47011 Valladolid, Spain.
Abstract:
The genetic engineering of protein-based polymers is a method that enables, in an easy way, the design of complex and highly functional macromolecules. As examples of this approach, different molecular designs are presented, with increasing degree of complexity, showing how the controlled increase in their complexity yields (multi)functional materials with more selected and sophisticated properties. The simplest designs show interesting properties already, but the adequate introduction of given chemical functions along the polymer chain provides an opportunity to expand the range of properties to enhanced smart behavior and self-assembly. Finally, examples are given where those molecular designs further incorporate selected bioactivities in order to develop materials for the most cutting edge applications in biomedicine and nano(bio)technology.

