Iridoid constituents of Tarenna attenuata
Xian-Wen Yang1, Yan-Ling Ma, Hong-Ping He
1State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People's Republic of China.
Abstract:
Members of a rare type of iridoid with two alpha,beta-unsaturated acid units were isolated from the whole plant of Tarenna attenuata, including a new compound, tarennin (1), an extraction artifact, and seven new glucosides, tarenninosides A-G (2-8), together with two known iridoid glucosides, ixoside and 10-methylixoside. The structures of 1-8 were elucidated by analysis of spectroscopic data including HMQC, HMBC, 1H-1H COSY, and ROESY NMR spectra and by comparison with known analogues. Antioxidant and cytotoxic activities were evaluated for these 10 compounds, but none showed positive activity.
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