Related Experiment Video
Updated: Jul 8, 2026

12:30
Electric Cell-substrate Impedance Sensing for the Quantification of Endothelial Proliferation, Barrier Function, and Motility
Published on: March 28, 2014
Interactive cell modeling web-resource, iCell, as a simulation-based teaching and learning tool to supplement
1Biomedical Engineering & Research to Aid Persons with Disabilities Program, National Science Foundation, 4201 Wilson Boulevard, Suite 565, Arlington, VA 22230, USA. sdemir@memphis.edu
Annals of Biomedical Engineering
|June 24, 2006
Summary
iCell is an interactive website featuring JAVA-coded models of cardiac cells and neurons for physiology education. This simulation tool enhances learning and collaboration for students and scientists globally.
Area of Science:
- Biomedical Engineering
- Computational Biology
- Physiology Education
Background:
- Traditional physiology education can be enhanced with interactive tools.
- There is a need for accessible, simulation-based learning resources in cellular biology.
- Integrating research and education platforms can foster scientific collaboration.
Purpose of the Study:
- To develop and disseminate an interactive web-based platform, iCell, for cellular modeling.
- To provide a simulation-based tool for teaching and learning cellular physiology.
- To create a collaborative environment for scientists interested in cell membrane activities.
Main Methods:
- Developed iCell using JAVA-coded models of cardiac cells and neurons.
- Integrated interactive features allowing users to modify model parameters and view simulation results.
- Included a glossary of scientific terms to support learning.
Main Results:
- iCell successfully serves as a teaching and learning tool in graduate courses.
- The platform has been utilized by scientists in 17 countries for teaching, learning, and collaboration.
- iCell provides an interactive, platform-independent, and user-friendly resource for electrophysiology.
Conclusions:
- Interactive cell modeling websites like iCell significantly enhance physiology education.
- Simulation-based tools are valuable for both learning and scientific collaboration in biosciences.
- The continued advancement of simulation technologies will drive progress in engineering and sciences.

