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Updated: Aug 7, 2026

Safety Precautions and Operating Procedures in an (A)BSL-4 Laboratory: 1. Biosafety Level 4 Suit Laboratory Suite Entry and Exit Procedures
Published on: October 3, 2016
[Biological research and security institutes]
G Darsie1, A J Falczuk, I E Bergmann
1Centro Panamericano de Fiebre Aftosa, Organización Panamericana de la Salud/Organización Mundial de la Salud, P.O. Box 589, CEP: 20010-974, Rio de Janeiro, RJ, Brasil.
Abstract:
The threat of using biological material for ago-bioterrorist ends has risen in recent years, which means that research and diagnostic laboratories, biological agent banks and other institutions authorised to carry out scientific activities have had to implement biosafety and biosecurity measures to counter the threat, while carrying out activities to help prevent and monitor the accidental or intentional introduction of exotic animal diseases. This article briefly sets outthe basic components of biosafety and biosecurity, as well as recommendations on organisational strategies to consider in laboratories that support agro-bioterrorist surveillance and prevention programs.
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