Related Experiment Video
Updated: Aug 7, 2026

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
Published on: January 7, 2019
Should electroconvulsive therapy be an early consideration for suicidal patients?
Malini Patel1, Sangeeta Patel, Daniel W Hardy
1Rosalind Franklin University of Medicine and Science, Chicago Medical School, Chicago, IL, USA. dhs594j@dhs.state.il.us
Introduction:
This article describes a quality management project undertaken for the purpose of ensuring that the most appropriate patients were being selected for electroconvulsive therapy (ECT) at an 80-bed, state-operated, civil psychiatric facility for the seriously mentally ill.
Method:
Thirty mentally ill patients, including patients with comorbid substance abuse diagnoses, were treated with ECT. Pre-ECT and post-ECT scores on the 24-item Brief Psychiatric Rating Scale (BPRS-24) were compared with admission and discharge BPRS-24 scores of a control group treated with psychotropic medication.
Results:
ECT-treated patients demonstrated greater improvement in BPRS scores during a shorter period than did non-ECT-treated patients. Furthermore, the greatest improvement was seen in the areas of depression and expressed suicidal intent. An unanticipated result was that patients with comorbid substance abuse diagnoses treated with ECT showed the most improvement in these areas.
Conclusion:
ECT was shown to be particularly useful in the treatment of suicidally inclined depressed patients, suggesting that ECT should be an early consideration for suicidal patients.
Related Concept Videos
Electroconvulsive Therapy
Psychosis: Goals of Pharmacotherapy
Psychosurgery
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
Antidepressant Drugs: MAOIs and Other Agents
Mania and Antimanic Drugs: Overview
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias