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Membrane Transport Processes Analyzed by a Highly Parallel Nanopore Chip System at Single Protein Resolution
Published on: August 16, 2016
Passage times for unbiased polymer translocation through a narrow pore
Joanne Klein Wolterink1, Gerard T Barkema, Debabrata Panja
1Institute for Theoretical Physics, Universiteit Utrecht, Minnaertgebouw, Leuvenlaan 4, Postbus 80.195, 3508 TD Utrecht, The Netherlands.
Abstract:
We study the translocation process of a polymer in the absence of external fields for various pore diameters b and membrane thickness L. The polymer performs Rouse and reptation dynamics. The mean translocation time (tau(t)) that the polymer needs to escape from a cell and the mean dwell time (tau(d)) that the polymer spends in the pore during the translocation process obey scaling relations in terms of the polymer length N, L, and b/R(g), where R(g) is the radius of gyration for the polymer. We explain these relations using simple arguments based on polymer dynamics and the equilibrium properties of polymers.
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