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Disseminated blastomycosis in an infant
Catharine M Walsh1, Shaun K Morris, Jason C Brophy
1Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Canada. catherine.walsh@utoronto.ca
Abstract:
Blastomycosis is an uncommon life-threatening disease caused by the dimorphic fungus Blastomyces dermatitidis. Estimates of the percentage of cases occurring in children range from 2% to 11%, and it is exceedingly rare in individuals less than 1 year of age. We present the case of an otherwise healthy infant with disseminated blastomycosis acquired in Northern Ontario and a brief review of the pediatric literature.
Insights
Blastomycosis is a rare, severe fungal infection. This case study details disseminated blastomycosis in an infant from Northern Ontario, highlighting its extreme rarity in this age group.
Area of Science:
- Mycology
- Infectious Diseases
- Pediatrics
Background:
- Blastomycosis is a life-threatening systemic infection caused by the dimorphic fungus *Blastomyces dermatitidis*.
- Pediatric cases of blastomycosis are uncommon, estimated between 2% and 11% of all cases.
- Infection in infants under 1 year of age is exceedingly rare.
Observation:
- This report details a case of disseminated blastomycosis in an otherwise healthy infant.
- The infant acquired the infection in Northern Ontario.
- This presentation is unusual given the patient's age and the rarity of blastomycosis in this demographic.
Findings:
- The case demonstrates that disseminated blastomycosis can occur in infants, even in the absence of known risk factors.
- The geographic location, Northern Ontario, is an endemic area for *Blastomyces dermatitidis*.
- Review of pediatric literature reveals limited data on infant blastomycosis.
Implications:
- This case underscores the importance of considering blastomycosis in the differential diagnosis of severe infections in infants, particularly in endemic regions.
- Early recognition and treatment are crucial for managing this rare but severe pediatric condition.
- Further research is needed to understand the epidemiology and clinical presentation of blastomycosis in very young children.
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