Related Experiment Video
Updated: Aug 7, 2026

10:45
Non-invasive Imaging of Disseminated Candidiasis in Zebrafish Larvae
Published on: July 30, 2012
Disseminated blastomycosis in an infant
Catharine M Walsh1, Shaun K Morris, Jason C Brophy
1Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Canada. catherine.walsh@utoronto.ca
The Pediatric Infectious Disease Journal
|June 29, 2006
Summary
Blastomycosis is a rare, severe fungal infection. This case study details disseminated blastomycosis in an infant from Northern Ontario, highlighting its extreme rarity in this age group.
Area of Science:
- Mycology
- Infectious Diseases
- Pediatrics
Background:
- Blastomycosis is a life-threatening systemic infection caused by the dimorphic fungus *Blastomyces dermatitidis*.
- Pediatric cases of blastomycosis are uncommon, estimated between 2% and 11% of all cases.
- Infection in infants under 1 year of age is exceedingly rare.
Observation:
- This report details a case of disseminated blastomycosis in an otherwise healthy infant.
- The infant acquired the infection in Northern Ontario.
- This presentation is unusual given the patient's age and the rarity of blastomycosis in this demographic.
Findings:
- The case demonstrates that disseminated blastomycosis can occur in infants, even in the absence of known risk factors.
- The geographic location, Northern Ontario, is an endemic area for *Blastomyces dermatitidis*.
- Review of pediatric literature reveals limited data on infant blastomycosis.
Implications:
- This case underscores the importance of considering blastomycosis in the differential diagnosis of severe infections in infants, particularly in endemic regions.
- Early recognition and treatment are crucial for managing this rare but severe pediatric condition.
- Further research is needed to understand the epidemiology and clinical presentation of blastomycosis in very young children.
Related Concept Videos
Cryptococcal Meningitis
Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Rocky Mountain Spotted Fever
Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
Pulmonary Tuberculosis III
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
Fungal Phylum Microsporidia
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
Cytomegalovirus Disease
Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
Pulmonary Tuberculosis II
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
