Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

TRP channels and Ca2+ signaling.

Baruch Minke1

  • 1Department of Physiology and the Kühne Minerva Center for Studies of Visual Transduction, The Hebrew University of Jerusalem, Jerusalem 91120, Israel. minke@md.huji.ac.il

Cell Calcium
|June 30, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Addendum to Nociception and pain in humans lacking a functional TRPV1 channel.

The Journal of clinical investigation·2026
Same author

Cholesterol inhibits capsaicin activation of the TRPV1 channel.

Channels (Austin, Tex.)·2026
Same author

Human Mutations in the TRPV1 Channel: Implications for Noxious Cold Sensation.

Annual review of pharmacology and toxicology·2025
Same author

Inhibition of TRPV1 by an antagonist in clinical trials is dependent on cholesterol binding.

Cell calcium·2024
Same author

The pioneering use of the PDA phenotype by Bill Pak for screening a network of phototransduction genes and the associated signaling pathways.

Journal of neurogenetics·2024
Same author

Membrane lipid modulations by methyl-β-cyclodextrin uncouple the Drosophila light-activated phospholipase C from TRP and TRPL channel gating.

The Journal of biological chemistry·2023

Transient receptor potential (TRP) channels are vital for sensory systems and cell function, making them key targets for treating diseases and pain. Research is rapidly advancing, yet fundamental understanding, like TRP channel gating, remains an open area.

Area of Science:

  • Biomedicine
  • Ion Channel Research
  • Cellular Physiology

Background:

  • Transient receptor potential (TRP) channels are increasingly recognized for their roles in sensory systems and cellular functions.
  • Dysfunction of TRP channels is implicated in various diseases, including inflammatory pain and genetic disorders.
  • TRP channels are crucial components in neurons, epithelial, blood, and smooth muscle cells.

Purpose of the Study:

  • To highlight the growing importance and emerging status of TRP channel research in biomedicine.
  • To present recent, often unpublished, findings from leading investigators in the TRP channel field.
  • To foster discussion and collaboration within the TRP channel research community.

Main Methods:

  • The study is based on presentations and discussions from the Minerva-Gentner Symposium on TRP channels and Ca(2+) signaling.

Related Experiment Videos

  • Investigators shared their latest research findings and insights into TRP channel function.
  • Informal discussions among symposium participants facilitated knowledge exchange.

    • Main Results:

    • Significant progress has been made in understanding TRP channels, as evidenced by symposium presentations.
    • TRP channel research is a rapidly developing field with major implications for human health.
    • Despite advancements, fundamental aspects, such as the gating mechanisms of TRP channels, remain largely unsolved.

    Conclusions:

    • The TRP channel field is a dynamic and expanding area of biomedical research.
    • TRP channels represent promising therapeutic targets for a range of diseases and conditions.
    • Further research is needed to fully elucidate the complex mechanisms governing TRP channel function.