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Updated: Aug 4, 2026
10:15
Intracerebroventricular Viral Injection of the Neonatal Mouse Brain for Persistent and Widespread Neuronal Transduction
Published on: September 15, 2014
Viral infections in the developing and mature brain
1Department of Neurosurgery, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA.
Trends in Neurosciences
|June 30, 2006
Summary
Viral infections can cause brain dysfunction. This review explores how various RNA and DNA viruses, like poliovirus and cytomegalovirus, impact neurological health in different age groups.
Area of Science:
- Neuroscience
- Virology
- Infectious Diseases
Background:
- Viral infections are a significant cause of neurological dysfunction.
- Different viruses exhibit varying genetic material (RNA/DNA) and genome sizes.
- The impact of viral neuroinvasion differs between developing and adult brains.
Purpose of the Study:
- To provide an overview of neurovirology.
- To discuss the contribution of viral infections to brain diseases.
- To highlight the complexity of viral-induced neurological disorders.
Main Methods:
- Literature review of neurovirology.
- Analysis of viral genetic material and genome size.
- Comparison of viral neuroinvasion effects in different age groups.
Main Results:
- Picornaviruses (RNA) infect motor neurons.
- Cytomegalovirus (DNA) causes developmental neurological issues.
- Viral neuroinvasion presents complex challenges in understanding brain disease.
Conclusions:
- Viral infections are a critical factor in neurological dysfunction.
- Understanding neurovirology requires appreciating viral diversity and impact.
- Further research is needed to address viral contributions to brain disorders.
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