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Acquired cardiac hypertrophy with outflow tract obstruction in a patient with severe Takayasu arteritis

Senay Funda Biyikoglu1, Meltem Ege, Mehmet Birhan Yilmaz

  • 1Yuksek Ihtisas Hospital, Cardiology Clinic, Sihhiye, Ankara, Turkey. fundabiyikoglu@yahoo.com

The International Journal of Cardiovascular Imaging
|June 30, 2006
PubMed

Insights

Takayasu arteritis rarely involves coronary arteries, and even more rarely causes secondary cardiac hypertrophy with outflow tract obstruction. This case highlights these uncommon associations in a patient diagnosed 10 years prior.

Area of Science:

  • Cardiovascular Medicine
  • Rheumatology
  • Internal Medicine

Background:

  • Takayasu arteritis is a rare, large-vessel vasculitis affecting the aorta and its branches.
  • Coronary artery involvement in Takayasu arteritis is infrequent.
  • Secondary cardiac hypertrophy leading to outflow tract obstruction is an uncommon complication.

Observation:

  • A patient with a 10-year history of Takayasu arteritis presented with findings suggestive of cardiac complications.
  • Investigations revealed significant coronary artery involvement.
  • The patient also exhibited severe cardiac hypertrophy causing outflow tract obstruction.

Findings:

  • The case confirms the rare association of Takayasu arteritis with coronary artery disease.
  • Obstructive cardiac hypertrophy secondary to Takayasu arteritis was definitively identified.
  • The diagnostic investigations successfully ascertained the extent of vascular and cardiac involvement.

Implications:

  • This case underscores the importance of considering cardiac complications in long-standing Takayasu arteritis.
  • Early recognition of coronary involvement and obstructive cardiomyopathy is crucial for timely management.
  • Further research may elucidate the mechanisms linking Takayasu arteritis to severe cardiac sequelae.

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