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Characterization of the variation between batches of Fast-Flo lactose using low frequency dielectric spectroscopy
D Q Craig1, C F Davies, J C Boyd
1School of Pharmacy, University of London, UK.
The Journal of Pharmacy and Pharmacology
|June 1, 1991
Abstract:
The dielectric response of four batches of lactose has been measured over a frequency range of 10(4) to 10(-2) Hz. The spectra corresponding to three of the batches were identical, while the fourth showed a marked reduction in response. This particular batch has also been reported to exhibit longer disintegration times than the other three when formulated as a tablet. The potential use of dielectric spectroscopy as a means of screening batches of pharmaceutical materials is discussed.