Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Fibertract segmentation in position orientation space from high angular resolution diffusion MRI.

Patric Hagmann1, Lisa Jonasson, Thomas Deffieux

  • 1Department of Radiology, Lausanne University Hospital (CHUV), Switzerland. Patric.hagmann@epfl.ch

Neuroimage
|July 4, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

High-resolution whole-brain magnetic resonance spectroscopic imaging in youth at risk for psychosis.

Imaging neuroscience (Cambridge, Mass.)·2026
Same author

The microstructure-weighted human connectome: network properties and structure-function correlations across spatial scales.

bioRxiv : the preprint server for biology·2026
Same author

Myo-inositol concentration in the medial prefrontal cortex is associated with changes in brain white matter microstructure in early psychosis.

Translational psychiatry·2026
Same author

Normative T<sub>1</sub> and T<sub>2</sub> Brain Atlases Across the Adult Lifespan in a Chinese Cohort: Multicenter Quantitative MRI Benchmarks for Ageing and Neurodegenerative Research.

Human brain mapping·2026
Same author

Introducing a translationally relevant mouse model of radiosurgery-induced unilateral hearing loss.

Frontiers in neuroscience·2026
Same author

Altered structural connectivity in epilepsy with myoclonic atonic seizures.

Epilepsy research·2026
Same journal

Segmentation of the parasagittal dura mater on multi-center 3D-FLAIR MRI.

NeuroImage·2026
Same journal

Spatial frequency channels implement a mental ruler in spatial vision.

NeuroImage·2026
Same journal

Exploring the Link Between Intravoxel Incoherent Motion Measured Brain Diffusivity During Wakefulness and Sleep Macrostructure in the Elderly.

NeuroImage·2026
Same journal

Closed-loop adaptation of transcranial magnetic stimulation intensity with electroencephalography feedback.

NeuroImage·2026
Same journal

Volumetric postmortem MRI of the medial temporal lobe in Alzheimer's disease and related disorders: methodological advances and implications for in vivo biomarker development.

NeuroImage·2026
Same journal

Neural responses to equity and inequity when receiving vicarious rewards for self and charity during adolescence.

NeuroImage·2026
See all related articles

This study introduces a novel segmentation approach for identifying white matter tracts in diffusion MRI. By treating tracts as regions of intense, coherent diffusion in a 5D space, this method offers advantages over traditional tractography.

Area of Science:

  • Neuroimaging
  • Medical Image Analysis
  • Computational Neuroscience

Background:

  • Standard diffusion MRI tract identification relies on tractography, which traces lines of coherent diffusion.
  • Tract identification is typically a selection process based on predefined criteria applied to these traced lines.

Purpose of the Study:

  • To investigate fibertract identification as a segmentation task rather than a line-tracing problem.
  • To develop and evaluate a novel method for segmenting white matter tracts in diffusion MRI data.

Main Methods:

  • Formulating fibertract identification as a segmentation problem in a five-dimensional position-orientation space.
  • Adapting a hidden Markov random field (HMRF) framework to this high-dimensional, non-Euclidean space.
  • Utilizing a back-projection technique, similar to maximum intensity projection, for 3D representation.

Related Experiment Videos

Main Results:

  • Successfully segmented well-known white matter tracts, including cerebellar peduncles, corticospinal tract, and association bundles.
  • Demonstrated the ability to handle naturally crossing tracts within the segmentation framework.
  • The method is not biased by human intervention, unlike some tractography approaches.

Conclusions:

  • Fibertract identification can be effectively achieved through image segmentation in a 5D position-orientation space.
  • This novel segmentation approach offers potential advantages over classical tractography, particularly in handling complex white matter architectures.
  • The method shows promise for more robust and automated white matter tract analysis in diffusion MRI.