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Acute osteomyelitis in congenital hypofibrinogenemia
Sumana Datta Kanjilal1, S Bagchi
1Midnapore Medical College, Paschim Medinipur, West Bengal. himadreedatta@yahoo.com
Indian Journal of Pediatrics
|July 4, 2006
Summary
Congenital hypofibrinogenemia can cause joint swelling due to acute osteomyelitis, not just bleeding. Prompt treatment of osteomyelitis and hypofibrinogenemia led to a positive outcome in an infant.
Area of Science:
- Pediatrics
- Hematology
- Infectious Diseases
Background:
- Congenital hypofibrinogenemia is a rare bleeding disorder.
- Joint swelling in infants can be multifactorial.
Observation:
- A 10-month-old infant presented with fever, left knee pain, and swelling, along with bruising.
- Radiological findings suggested acute osteomyelitis.
- Laboratory tests revealed low fibrinogen levels and Staphylococcus aureus bacteremia.
Findings:
- The infant was diagnosed with acute osteomyelitis and congenital hypofibrinogenemia.
- Treatment for both conditions resulted in significant improvement.
- Coagulase-positive Staphylococcus aureus was identified as the causative agent of bacteremia.
Implications:
- This case highlights that joint swelling in congenital hypofibrinogenemia may indicate acute osteomyelitis.
- It underscores the importance of considering infection in infants with bleeding disorders and joint effusions.
- Early diagnosis and combined treatment are crucial for favorable outcomes.
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