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Updated: Aug 7, 2026

Applying Cheminformatics to Develop a Structure Searchable Database of Analytical Methods
Published on: June 6, 2025
Collaborative development of the Arrowsmith two node search interface designed for laboratory investigators
Neil R Smalheiser1, Vetle I Torvik, Amanda Bischoff-Grethe
1Department of Psychiatry and Psychiatric Institute, University of Illinois, MC912, 1601 W, Taylor Street, Chicago, IL 60612, USA. neils@uic.edu
Abstract:
Arrowsmith is a unique computer-assisted strategy designed to assist investigators in detecting biologically-relevant connections between two disparate sets of articles in Medline. This paper describes how an inter-institutional consortium of neuroscientists used the UIC Arrowsmith web interface http://arrowsmith.psych.uic.edu in their daily work and guided the development, refinement and expansion of the system into a suite of tools intended for use by the wider scientific community.

