[NSAIDs-induced colopathy with diaphragm-like strictures. Case report.]
Hjœrtur Fr Hjartarson1, Nick Cariglia, Jóhannes Bjœrnsson
1Akureyri University Hospital, 600 Akureyri, Iceland. hjortur@fsa.is.
Abstract:
A sixty-eight-year old male with osteoarthritis was admitted for elective hip replacement. Routine preoperative tests found the patient to be anemic and the operation was postponed. Colonoscopy revealed diaphragm-like strictures and ulcerations in the right colon. A right hemicolectomy was performed. It is believed that the lesions were due to the use of non-steroidal anti-inflammatory drugs (NSAIDs), as the patient had been taking diclofenac for the preceding eighteen months due to hip pain. At the time of this diagnosis, apparoximately thirty cases of colopathy with diaphragm-like strictures due to NSAID use had been reported worldwide. It is likely that with increasing use of slow-release and enterocoated preparations of NSAIDs, the number of similar cases will increase.
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