[NSAIDs-induced colopathy with diaphragm-like strictures. Case report.]
Hjœrtur Fr Hjartarson1, Nick Cariglia, Jóhannes Bjœrnsson
1Akureyri University Hospital, 600 Akureyri, Iceland. hjortur@fsa.is.
Laeknabladid
|July 5, 2006
Summary
Non-steroidal anti-inflammatory drug (NSAID) use can cause rare but serious colon damage, including diaphragm-like strictures. This case highlights the importance of considering NSAID-induced colopathy in patients with relevant symptoms.
Area of Science:
- Gastroenterology
- Pharmacology
Context:
- A 68-year-old male with osteoarthritis presented for hip replacement.
- Routine tests revealed anemia, leading to surgery postponement.
Purpose:
- To report a case of NSAID-induced colopathy with diaphragm-like strictures.
- To raise awareness of this rare gastrointestinal complication.
Summary:
- Colonoscopy identified diaphragm-like strictures and ulcerations in the right colon.
- The patient had a history of diclofenac use for hip pain over 18 months.
- A right hemicolectomy was performed to address the colonic lesions.
Impact:
- This case adds to the approximately 30 reported worldwide cases of NSAID-induced diaphragm-like strictures.
- Increasing use of slow-release and enterocoated NSAIDs may lead to a rise in similar cases.
- Highlights the need for vigilance regarding NSAID-induced gastrointestinal toxicity.
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