Solution NMR of membrane proteins: practice and challenges

Charles R Sanders1, Frank Sönnichsen

  • 1Department of Biochemistry and Center for Structural Biology, Vanderbilt University, Nashville, TN, 37232-8725, USA. chuck.sanders@vanderbilt.edu

Summary

Solution Nuclear Magnetic Resonance (NMR) methods are applied to multispan integral membrane proteins to determine their global folds. This review details practical techniques and challenges for studying these proteins within lipid bilayers.

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