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Cerebrospinal fluid beta-2-microglobulin in HIV-1 infection, as a marker of neurological involvement
O Perrella1, P B Carrieri, E Izzo
1D. Cotugno Hospital for Infectious Diseases, Naples, Italy.
Neurological Research
|June 1, 1991
Abstract:
Cerebrospinal fluid (CSF) and serum concentration of beta-2-microglobulin (beta-2-m) were evaluated in 30 patients in various stages of HIV-1 infection. CSF beta-2-m and CSF/serum ratio were significantly higher in patients with neurological complications respect to asymptomatic subjects. These findings indicate that CSF beta-2-m and CSF/serum ratio may be a useful marker of neurological involvement in HIV-1 infection.