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Aortic valve repair for congenital abnormalities of the aortic valve
Mohammed A Quader1, Geoffrey L Rosenthal, Athar M Qureshi
1Department of Pediatric and Congenital Heart Surgery/M41, Children's Hospital, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
Insights
Aortic valve repair for congenital heart defects offers a promising alternative to valve replacement, avoiding anticoagulation and preserving the native valve. Most patients avoided reoperation, maintaining good long-term outcomes.
Area of Science:
- Cardiovascular Surgery
- Pediatric Cardiology
- Congenital Heart Disease
Background:
- Congenital aortic valve disease presents challenges due to the limitations of valve replacement.
- Repairing and preserving the native aortic valve is a potential alternative for these patients.
Purpose of the Study:
- To evaluate the efficacy and outcomes of aortic valve repair in patients with congenital abnormalities.
- To assess the need for reoperation, anticoagulation, and long-term survival after aortic valve repair.
Main Methods:
- Retrospective review of aortic valve repair data from a single institution (1993-2001).
- Analysis of patient demographics, aortic valve lesions, repair techniques, and follow-up data.
Main Results:
- 56 patients underwent aortic valve repair, with mixed aortic stenosis/insufficiency and pure aortic insufficiency being the most common lesions.
- Hospital survival was 98%, with no patient discharged on anticoagulation. At a median follow-up of 37 months, 95% of patients remained alive.
- 84% experienced reintervention-free survival, with a minority requiring subsequent aortic valve replacement or repeat repair.
Conclusions:
- Aortic valve repair for congenital abnormalities successfully avoided reoperation in most patients.
- The procedure eliminated the need for anticoagulation and maintained the native valve's growth potential.
- Subsequent valve deterioration may necessitate repeat aortic valve repair or replacement.
Background:
Due to shortcomings of any valve replacement, repairing and retaining the native valve may be beneficial for congenital aortic valve disease.
Methods:
Retrospective review of data and follow-up of aortic valve repair from a single institution.
Results:
From 1993 to 2001, 56 patients underwent aortic valve repair [median age 13.4 years (range 1 day to 45 years)]. The predominant aortic valve lesion was mixed aortic stenosis/aortic insufficiency 25 (45%), aortic insufficiency 24 (43%) and aortic stenosis 7 (13%). Repair techniques included sub-commissural plication 36 (64%), commissurotomy 24 (43%), cusp plication 15 (27%), pericardial patch cusp extension 8 (14%) and resuspension of commissures 4 (7%). Most patients (88%) required a combination of techniques; 61% required additional procedures. Hospital survival was 55/56 [98%; (95% CI 91-100%)] no patient was discharged on anticoagulation for aortic valve pathology. Fifty-three patients [95%; (95% CI 85-98%)] remain alive after a median follow-up of 37 months; four survivors required aortic valve replacement and two required repeat aortic valve repair [84%; (95% CI 72-91%) reintervention-free survival].
Conclusions:
(1) In this study, aortic valve repair for congenital abnormalities avoided reoperation in the majority of patients, avoided anticoagulation and retained growth potential of the valve. (2) Repeat aortic valve repair or replacement was used to treat subsequent valve deterioration.
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