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[Supercritical fluid extraction of paeonol from Liuwei Dihuang pill]
1Zhejiang Pharmaceutical College, Ningbo, China.
Abstract
Objective:
To study the method of extraction of active ingredient from complex Chinese patent medicine.
Method:
Supercritical fluid extraction (SFE) has been used to extract paeonol from Liuwei Dihuang pill and HPLC was used to analyze the extracts.
Result:
The methanol modified supercritical CO2 (0.4 mL x min(-1)) can effectively extract paeonol from Liuwei Dihuang pill.
Conclusion:
SFE-HPLC method of off-line for analysis of extract was simple, quick and accurate.