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Posterior circulation ischemic stroke in Korean population

J-H Lee1, S-J Han, Y-H Yun

  • 1Department of Neurology, College of Medicine, Hallym University, Anyang City, South Korea.

European Journal of Neurology
|July 13, 2006
PubMed

Insights

This study analyzed posterior circulation ischemic stroke (PCS) in Koreans, finding large artery disease and hypertension were common. PCS characteristics in this population differ from Caucasian data.

Area of Science:

  • Neurology
  • Stroke Medicine
  • Epidemiology

Background:

  • Posterior circulation ischemic stroke (PCS) is a significant cause of morbidity and mortality.
  • Understanding the specific characteristics of PCS in diverse populations is crucial for targeted prevention and treatment strategies.

Purpose of the Study:

  • To investigate the demographic features, risk factors, stroke subtypes, lesion distributions, and clinical outcomes of PCS in the Korean population.
  • To compare these characteristics with those reported in Caucasian populations.

Main Methods:

  • Retrospective review of 591 consecutive PCS patients from the Hallym Stroke Registry (HSR) between January 1996 and July 2002.
  • Analysis included patient demographics, risk factors (hypertension, cardioembolic sources), stroke subtypes (large artery disease, small vessel disease, cardioembolism), infarct locations, and clinical outcomes (hospital mortality, discharge status).

Main Results:

  • PCS constituted 39.8% of all ischemic strokes in the study cohort.
  • The most common risk factor was hypertension (69.9%), while cardioembolic sources were infrequent (11.0%).
  • Large artery disease (50.0%) was the predominant stroke subtype, followed by small vessel disease (33.8%). Infarcts were most commonly located in the middle territory (36.5%).
  • Hospital mortality rate was 4.1%, and outcomes were comparable to anterior circulation stroke (ACS).

Conclusions:

  • The etiology and lesion topography of PCS in the Korean population exhibit distinct patterns compared to Caucasian populations, notably with a higher prevalence of large artery disease.
  • Hypertension is a major risk factor, and cardioembolic sources are less common in Korean PCS patients.
  • These findings underscore the need for population-specific approaches in managing posterior circulation ischemic stroke.

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