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[(DPEPhos)(bcp)Cu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst
Published on: May 21, 2019
Novel reaction pathways for 2-pyridone [4+4] photoadducts
Peiling Chen1, Yanping Chen, Patrick J Carroll
1Department of Chemistry, Temple University, Philadelphia, Pennsylvania 19010, USA.
Abstract:
[Structure: see text] Transannular ring closure of a pyridone-furan [4+4] photoadduct has been evaluated in a model system. A combination of nitrogen substitution and an isopropyl group gave full control of the four new stereogenic centers. Chlorination transformed the 1,5-cyclooctadiene to a [4.2.0] ring system instead of to the expected [3.3.0] ring system. Changing an alkene to an enone suppressed this pathway and led to a new rearrangement, converting the 5-8-5 ring system to a 6-7-5 system.
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