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Updated: Aug 7, 2026

The Optokinetic Response as a Quantitative Measure of Visual Acuity in Zebrafish
Published on: October 9, 2013
Normal age-related sensitivity loss for a variety of visual functions throughout the visual field
Stuart K Gardiner1, Chris A Johnson, Paul G D Spry
1Discoveries in Sight Research Labs, Devers Eye Institute, Portland, Oregon 97208-3950, USA.
Purpose:
The purpose of this study is to compare the rate of age-related decline, the magnitude of practice effects, and test-retest variability among normal subjects using six different tests of visual function.
Methods:
One hundred normal subjects aged between 20 and 85 were enrolled in the study. Six visual field test procedures were used consisting of standard automated perimetry (SAP), short wavelength automated perimetry (SWAP), temporal modulation perimetry (TMP), frequency-doubling technology perimetry (FDT), detection acuity perimetry (DAP),and resolution acuity perimetry (RAP). To facilitate direct comparison, the results for each test were divided by that test's estimated dynamic range.
Results:
Of the three tests used clinically most commonly, SWAP exhibited the greatest aging and practice effects and test-retest variability followed by FDT with SAP exhibiting the least. RAP was the most variable test followed by TMP.
Conclusions:
These results should be taken into account when evaluating glaucomatous loss using different functional tests and when comparing the performance, predictive power, and speed of detection of the different tests.
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