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Ectopic lingual thyroid tissue and acquired hypothyroidism: case report.

C Cappelli1, E Gandossi, D Cumetti

  • 1Section of Endocrinology, University of Brescia, Italy. cappi.tsh@libero.it

Annales D'Endocrinologie
|July 15, 2006
PubMed
Summary

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This study reports an extremely rare case of ectopic thyroid tissue alongside a normally located thyroid gland in a hypothyroid patient. Management involved L-thyroxine replacement, highlighting the importance of understanding embryological origins and clinical approaches.

Area of Science:

  • Endocrinology
  • Medical Case Reports
  • Embryology

Background:

  • Ectopic thyroid tissue, particularly with a normally positioned gland, is exceptionally rare.
  • Hypothyroidism symptoms prompted the investigation of a 38-year-old woman.
  • Understanding the embryological development of the thyroid is crucial for diagnosing ectopic presentations.

Observation:

  • The patient presented with clinical hypothyroidism and elevated anti-thyroid antibodies.
  • Neck ultrasonography revealed Hashimoto thyroiditis in the thyroid bed.
  • Thyroid scintigraphy exclusively identified a lingual thyroid, indicating ectopic tissue.

Findings:

  • The case demonstrates the coexistence of a normally located thyroid (affected by Hashimoto's) and a functional ectopic lingual thyroid.

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  • Diagnosis was confirmed through hormonal assays, ultrasonography, and scintigraphy.
  • Successful management was achieved with L-thyroxine hormone replacement therapy.

    • Implications:

    • This case underscores the diagnostic challenges and rare embryological variations in thyroid development.
    • It emphasizes the need for comprehensive imaging and diagnostic workup in suspected ectopic thyroid conditions.
    • The findings contribute to the literature on the clinical management of dual ectopic and orthotopic thyroid tissue.