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Image-guided pleural biopsy: diagnostic yield and complications
R E Benamore1, K Scott, C J Richards
1Department of Radiology and Department of Histopathology, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester, UK. rachelbenamore@doctors.org.uk
Clinical Radiology
|July 18, 2006
Summary
Image-guided pleural biopsy is a safe and effective procedure for diagnosing malignant pleural disease, showing a 76% sensitivity with minimal complications. This method offers higher diagnostic accuracy than traditional needle biopsies.
Area of Science:
- Pulmonology
- Radiology
- Pathology
Background:
- Pleural biopsy and cytology are standard diagnostic tools for pleural diseases.
- Image-guided pleural biopsy may offer improved sensitivity for diagnosing pleural malignancy compared to traditional methods.
- There is a need to document the complication rate and diagnostic yield of image-guided pleural biopsies.
Purpose of the Study:
- To evaluate the complication rate and diagnostic yield of image-guided pleural biopsies.
- To compare the effectiveness of image-guided pleural biopsy with conventional methods for diagnosing malignant pleural disease.
Main Methods:
- Retrospective review of radiology and pathology databases for image-guided pleural biopsies (CT and ultrasound) from 2001-2004.
- Review of imaging, histology, and patient records for complications, pleural presence, and tissue adequacy.
- Analysis of diagnostic information from multidisciplinary team databases.
Main Results:
- 85 image-guided pleural biopsies were performed on 82 patients over 4 years (80 CT, 5 US).
- Pneumothorax rate was 4.7% with no need for chest drains or transfusions.
- Diagnostic sensitivity and specificity for malignancy were 76% and 100%, respectively, with 12% inadequate tissue samples.
Conclusions:
- Image-guided pleural biopsy is a safe procedure with a low complication rate.
- This technique demonstrates higher sensitivity for diagnosing malignant pleural disease than previously reported for reverse cutting needle biopsies.
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