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Effect of haloperidol decanoate on the cardiovascular system
S Kaneko1, J G Edwards, A Goldie
1Department of Neuropsychiatry, Hirosaki University School of Medicine, Japan.
The Japanese Journal of Psychiatry and Neurology
|March 1, 1991
Abstract:
Rapid speed electrocardiograms were recorded in 13 chronic schizophrenic patients before, and at regular intervals during a six-month trial of haloperidol decanoate. Measurements of conduction intervals in the EEG were carried out blind to patient and to assessment interval. No significant changes in heart rate; PR, QRS on QTc intervals; or T-wave height were found. Neither was there a significant change in the blood pressure. The findings confirm that haloperidol does not have clinically relevant cardiac effects when given in therapeutic doses to physically healthy individuals.