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[The effect of actovegin on spermatogenesis in white male rats upon clinical death modeling]
Eksperimental'Naia I Klinicheskaia Farmakologiia
|July 19, 2006
Abstract:
The indices of spermatogenesis in white male rats have been studied after clinical death modeling by means of cardiac fascicle compression. The model disorder leads to a reliable decrease in the number of spermatogenic epithelium, Sertoli cells, and Leydig cells in the testicles. A single injection of actovegin (10 mg/kg) during the reanimation period decreases the disturbances in spermatogenesis and leads to its complete recovery by the 45th day of postreanimation period.