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Hypophosphatemia in children hospitalized within an intensive care unit
Fernanda Souza de Menezes1, Heitor Pons Leite, Juliana Fernandez
1Pediatric Intensive Care Unit, Hospital São Paulo, São Paulo, Brazil.
Insights
Hypophosphatemia, a low phosphate level, is common in critically ill children. This study found it occurred in 76% of pediatric intensive care unit patients and was linked to malnutrition.
Area of Science:
- Pediatric Intensive Care
- Critical Care Medicine
- Pediatric Nephrology
Background:
- Hypophosphatemia is a common electrolyte disturbance in critically ill patients.
- Identifying risk factors and outcomes is crucial for managing this condition in pediatric intensive care units (PICUs).
Purpose of the Study:
- To determine the prevalence of hypophosphatemia in children admitted to a PICU.
- To identify potential risk factors and outcome measures associated with hypophosphatemia in this population.
Main Methods:
- Retrospective analysis of data from 42 children admitted to a single PICU over one year.
- Serum phosphorus levels measured on day 3 of admission; hypophosphatemia defined as <3.8 mg/dL.
Main Results:
- Hypophosphatemia was detected in 32 children (76%).
- A significant association was found between hypophosphatemia and malnutrition (P = .04).
- No significant associations were found between hypophosphatemia and mortality, PICU length of stay, or mechanical ventilation duration.
Conclusions:
- Hypophosphatemia is a frequent finding in critically ill children within the PICU setting.
- Malnutrition is a significant associated factor for hypophosphatemia in this patient group.
Abstract:
The aims of this study were to estimate the occurrence of hypophosphatemia and to identify potential risk factors and outcome measures associated with this disturbance in children admitted to a pediatric intensive care unit. Data concerning 42 children admitted consecutively to 1 pediatric intensive care unit over a 1-year period were examined. Serum phosphorus levels were measured on the third day of admission, where levels below 3.8 mg/dL were considered indicative of hypophosphatemia. Hypophosphatemia was found in 32 children (76%), and there was a significant association between this disturbance and malnutrition (P = .04). Of the potential risk factors such as sepsis, diuretic/steroid therapy, starvation (over 3 days), and Pediatric Index of Mortality, none discriminated for hypophosphatemia. There were no associations between hypophosphatemia and mortality, length of stay in the pediatric intensive care unit, or time on mechanical lung ventilation. Hypophosphatemia was a common finding in critically ill children and was associated with malnutrition.
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