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Updated: Aug 7, 2026

Image-guided In Vivo Tracking of Transplanted Distal Lung Epithelial Progenitor Cells for Pulmonary Fibrosis Using Magnetic Particle Imaging
Published on: June 27, 2025
Stem cells--potential for repairing damaged lungs and growing human lungs for transplant
Anne E Bishop1, Helen J Rippon
1Imperial College Faculty of Medicine, Tissue Engineering & Regenerative Medicine Centre, Chelsea & Westminster Campus, Fulham Road, London, SW10 9NH, UK. a.e.bishop@imperial.ac.uk
Abstract:
Repair or regeneration of defective lung epithelium would be of great therapeutic potential. It is estimated by the British Lung Foundation that 1 in 7 people in the UK is affected by a lung disease and that 1 in 4 admissions to children's wards are as a result of respiratory problems. Potential cellular sources for the regeneration of lung tissue in vivo or lung tissue engineering in vitro include endogenous pulmonary epithelial stem cells, extrapulmonary circulating stem cells and embryonic stem cells. This article discusses the potential role of each of these stem cell types in future approaches to the treatment of lung injury and disease.
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