Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Shear modulus reconstruction in dynamic elastography: time harmonic case.

Eunyoung Park1, Antoinette M Maniatty

  • 1Department of Mechanical, Aerospace and Nuclear Engineering, Rensselaer Polytechnic Institute, Troy, New York 12180, USA. parke@rpi.edu

Physics in Medicine and Biology
|July 25, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Oncolytic adenovirus co-expressing IL-12 and shVEGF potentiates immune checkpoint blockade for treatment of renal cell carcinoma: in vitro, organ-on-a-chip, and in vivo evaluation.

Molecular medicine (Cambridge, Mass.)·2026
Same author

Effects of a practitioner-led empowerment program for low-income social service recipients in South Korea: a quasi-experimental study.

Journal of Korean Academy of Nursing·2026
Same author

Feasibility of a short-term intensive home-based cognitive and physical training program for older adults: a single-arm pilot study.

BMC geriatrics·2026
Same author

Microfluidic profiling of suspension cell-metal adhesion at single-cell resolution under flow.

Lab on a chip·2026
Same author

Machine learning-based integration of transcriptome and digital pathology for predicting chemoresistance in muscle-invasive bladder cancer.

Experimental & molecular medicine·2026
Same author

Improved image reconstruction in coherent diffraction imaging using self-seeded XFEL pulses.

Journal of synchrotron radiation·2026
Same journal

Deep learning-based dose prediction to enhance planning efficiency in cervical brachytherapy with hybrid applicators.

Physics in medicine and biology·2026
Same journal

Corrigendum: Referenceless MR thermometry-a comparison of five methods (2017<i>Phys. Med. Biol</i>.<b>62</b>1-16).

Physics in medicine and biology·2026
Same journal

Corrigendum: Measured and Monte Carlo simulated electron backscatter to the monitor chamber for the varian TrueBeam linac (2016<i>Phys. Med. Biol</i>.<b>61</b>8779).

Physics in medicine and biology·2026
Same journal

Corrigendum: 3D range-modulator for scanned particle therapy: development, Monte Carlo simulations and experimental evaluation (2017<i>Phys. Med. Biol</i>.<b>62</b>7075).

Physics in medicine and biology·2026
Same journal

Recent progress in applications of computing to radiotherapy (ICCR 2016).

Physics in medicine and biology·2026
Same journal

Novel TMS coils designed using an inverse boundary element method.

Physics in medicine and biology·2026
See all related articles

This study introduces a direct inversion method to reconstruct soft tissue

Area of Science:

  • Biomechanics
  • Medical Imaging
  • Computational Mechanics

Background:

  • Accurate soft tissue characterization is crucial for medical diagnosis.
  • Existing methods for elastic shear modulus reconstruction often require boundary conditions or iterative processes.
  • Understanding tissue mechanics aids in disease detection and treatment planning.

Purpose of the Study:

  • To develop a direct, non-iterative inversion method for reconstructing the elastic shear modulus in soft tissues.
  • To investigate the impact of hydrostatic stress and noise on reconstruction accuracy.
  • To validate the method using simulated and experimental magnetic resonance (MR) data.

Main Methods:

  • Finite element discretization of elasto-dynamic equations for harmonic motion.

Related Experiment Videos

  • A novel procedure to eliminate the need for boundary conditions in the inverse problem.
  • Sensitivity analysis for detecting abnormal tissue regions and reconstruction with simulated and MR-measured data.

    • Main Results:

    • The direct inversion method successfully reconstructs the elastic shear modulus and hydrostatic stress.
    • The study quantifies the effects of hydrostatic stress and noise on reconstruction accuracy.
    • The algorithm demonstrates robust performance on simulated data and MR experimental data from a tissue phantom.

    Conclusions:

    • The proposed direct inversion approach offers a computationally efficient and accurate method for soft tissue shear modulus reconstruction.
    • The method's ability to reconstruct hydrostatic stress provides a more complete mechanical characterization.
    • This technique shows promise for non-invasive assessment of tissue mechanical properties in clinical settings.