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Related Concept Videos

What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
Cancers Originate from Somatic Mutations in a Single Cell02:21

Cancers Originate from Somatic Mutations in a Single Cell

Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...
Cancer Prevention02:59

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Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
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Cancers Originate from Somatic Mutations in a Single Cell02:21

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Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...
Cancer Prevention02:59

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Generation of Comprehensive Thoracic Oncology Database - Tool for Translational Research
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The evolution of the population-based cancer registry.

Donald M Parkin1

  • 1Clinical Trials Service Unit & Epidemiological Studies Unit, University of Oxford, Richard Doll Building, Old Road Campus, Oxford, OX3 7LF, UK. max.parkin@ctsu.ox.ac.uk

Nature Reviews. Cancer
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PubMed
Summary
This summary is machine-generated.

Cancer registries have evolved from tracking cancer patterns to aiding in patient care and control. This global review examines current cancer registration practices and their expanding roles worldwide.

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Area of Science:

  • Oncology
  • Public Health
  • Epidemiology

Background:

  • Cancer registration has a long history, originating in the early 20th century.
  • Early registries focused on describing cancer patterns and trends.
  • The scope has expanded significantly over time.

Purpose of the Study:

  • To review the current status of cancer registration practices globally.
  • To examine the evolving uses of cancer registries.
  • To highlight the international perspective on cancer registration.

Main Methods:

  • Literature review of cancer registration practices.
  • Analysis of the historical development and current roles of cancer registries.
  • International comparative assessment.

Main Results:

  • Cancer registries have grown substantially in number and scope since their inception.
  • Their functions have expanded from descriptive epidemiology to include survival analysis, patient care, and cancer control planning/evaluation.
  • Cancer registration is now a global activity with diverse applications.

Conclusions:

  • Cancer registration is a critical and expanding global activity.
  • Registries play a vital role in understanding cancer burden and improving cancer control.
  • The continuous evolution of registries supports comprehensive cancer management.