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Related Experiment Videos

Electrocardiographical case. A man found unconscious.

C Tan1, S Pillai, P G Manning

  • 1Accident and Emergency Department, Changi General Hospital, 2 Simei Street 3, Singapore 529889. camlyn_tan@cgh.com.sg

Singapore Medical Journal
|July 26, 2006
PubMed
Summary
This summary is machine-generated.

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Tricyclic antidepressant poisoning can cause specific ECG changes, including QTc prolongation and QRS widening. Lead aVR is crucial for diagnosing TCA toxicity, even when overlooked.

Area of Science:

  • Cardiology
  • Toxicology
  • Emergency Medicine

Background:

  • Tricyclic antidepressants (TCAs) are commonly prescribed but can cause life-threatening toxicity.
  • ECG is a critical tool for diagnosing TCA poisoning in emergency settings.

Observation:

  • A 25-year-old male presented with unconsciousness, indicative of severe poisoning.
  • Electrocardiography revealed characteristic signs of tricyclic antidepressant toxicity.

Findings:

  • Key ECG findings included sinus tachycardia, QTc prolongation, QRS widening, and right axis deviation.
  • Positive R waves in lead aVR were a unique and important diagnostic marker.

Implications:

  • This case underscores the diagnostic significance of lead aVR in identifying tricyclic antidepressant poisoning.

Related Experiment Videos

  • Prompt ECG interpretation guides immediate and appropriate treatment for TCA overdose.