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1Service de Chimie Analytique et Bromatologie, Faculté de Pharmacie de Grenoble, 38700 La Tronche, France.
Journal of Pharmaceutical and Biomedical Analysis
|January 1, 1983
Summary
This study reviews methods for detecting drugs in food, originating from animal treatments or feed additives. Accurate and rapid analytical techniques are crucial for ensuring food safety and preventing adverse health effects.
Area of Science:
- Food safety analysis
- Analytical chemistry
- Pharmacology in food production
Context:
- Drugs enter the food supply through animal therapeutics, zootechnical feed supplementation, and human food additives.
- The presence of pharmaceutical residues in food poses potential health risks to consumers.
- Ensuring the safety of the food supply necessitates robust methods for drug residue detection.
Purpose:
- To review and discuss methods for the quantitative determination of drugs in food and animal feed.
- To highlight the critical analytical requirements for drug determination: specificity, sensitivity, accuracy, and rapidity.
- To examine various analytical techniques applicable to drug residue analysis in food matrices.
Summary:
- The abstract discusses the sources of drug contamination in food, including veterinary medicines and feed supplements.
- It emphasizes the importance of analytical methods that are specific, sensitive, accurate, and rapid for drug determination.
- Spectroscopic, electrochemical, and chromatographic techniques are presented as key analytical approaches, with examples like ipronidazole and chloramphenicol.
Impact:
- Provides a foundation for developing and validating analytical methods for drug residues in food.
- Contributes to regulatory efforts aimed at safeguarding public health by controlling drug use in food-producing animals.
- Underscores the necessity of quality assurance in analytical testing to ensure reliable food safety data.