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Metabolic syndrome and gender differences in postprandial lipaemia
Genovefa D Kolovou1, Katherine K Anagnostopoulou, Antonis N Pavlidis
1First Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece. genkolovou@nail.gr
Background:
Postprandial hyperlipidaemia may be a predictor of vascular risk.
Design:
We evaluated postprandial lipaemia after an oral fat tolerance test (OFTT) in men (n=41) and women (n=21) with metabolic syndrome (MetS).
Methods:
Triglyceride (TG) levels were measured before and 2, 4, 6 and 8 h after the fat load.
Results:
Men showed a greater plasma TG response 8 h after the fat load (284+/-117 versus 224+/-126 mg/dl, P=0.029). Only fasting TG levels significantly predicted the TG area under the curve (AUC) and incremental AUC.
Conclusions:
Men had a more pronounced postprandial hypertriglyceridaemia and seem to have delayed TG clearance.
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