From worm genetic networks to complex human diseases

Role of Pbr1, a putative oxidoreductase, in the ER quality control and folding of yeast Fks1 glucan synthase.

Proceedings of the National Academy of Sciences of the United States of America·2026

Towards the construction of a virtual yeast.

Nature·2026

The novel antifungal agent NPD2560 perturbs the Rho1-centered signaling network to induce a cell wall integrity response.

Microbiology spectrum·2026

Orobas: A computational approach for scoring and analysis of quantitative chemical-genetic interactions from CRISPR-Cas9 screens.

STAR protocols·2026

Population-scale chemical response revealed by a barcoded yeast collection.

Nature communications·2026

Global genetic interaction network of a human cell maps conserved principles and informs functional interpretation of gene co-essentiality profiles.

Cell·2026

Enhancer control of promoter activity and variability via frequency modulation of clustered transcriptional bursts.

Nature genetics·2026

Pervasive interactions between exposures and polygenic risk can inform more effective clinical and behavioral interventions.

Nature genetics·2026

Multiscale analysis and functional validation of the cellular and genetic determinants of skeletal disease.

Nature genetics·2026

Graph-based pan-genome reveals structural variations associated with agronomic traits in mung bean.

Nature genetics·2026

Evolving patterns of co-mutations from tumor initiation to metastatic progression.

Nature genetics·2026

Metabolically and epigenetically reprogrammed splenic TRNP1<sup>hi</sup>CD8<sup>+</sup> T cells exacerbate liver fibrosis.

Nature genetics·2026

White Matter Functional Dysregulation in Amyotrophic Lateral Sclerosis: Machine Learning-Based Biomarkers and Transcriptomic Signatures.

Current neuropharmacology·2026

Combined bidirectional spinal cord stimulation for refractory neuropathic pelvic pain: a case report.

Frontiers in pain research (Lausanne, Switzerland)·2026

Neurovascular unit uncoupling in diabetic retinopathy: molecular mechanisms and stage-adapted therapeutic strategies.

Frontiers in endocrinology·2026

Late-onset ornithine transcarbamylase deficiency with neurological damage and serial brain multimodality monitoring: a case report.

Frontiers in medicine·2026

The influence of magnesium ions on the electrophysiological, analgesic, and BDNF-induced neuromodulation of morphine effects in diabetic rats.

Frontiers in pharmacology·2026

Risk factors of nasogastric tube removal failure in acute ischemic stroke patients: a 3-months follow-up cohort study at a single institute.

Frontiers in neurology·2026

Related Experiment Videos

From worm genetic networks to complex human diseases

Related Concept Videos

Role of Pbr1, a putative oxidoreductase, in the ER quality control and folding of yeast Fks1 glucan synthase.

Towards the construction of a virtual yeast.

The novel antifungal agent NPD2560 perturbs the Rho1-centered signaling network to induce a cell wall integrity response.

Orobas: A computational approach for scoring and analysis of quantitative chemical-genetic interactions from CRISPR-Cas9 screens.

Population-scale chemical response revealed by a barcoded yeast collection.

Global genetic interaction network of a human cell maps conserved principles and informs functional interpretation of gene co-essentiality profiles.

Enhancer control of promoter activity and variability via frequency modulation of clustered transcriptional bursts.

Pervasive interactions between exposures and polygenic risk can inform more effective clinical and behavioral interventions.

Multiscale analysis and functional validation of the cellular and genetic determinants of skeletal disease.

Graph-based pan-genome reveals structural variations associated with agronomic traits in mung bean.

Evolving patterns of co-mutations from tumor initiation to metastatic progression.

Metabolically and epigenetically reprogrammed splenic TRNP1<sup>hi</sup>CD8<sup>+</sup> T cells exacerbate liver fibrosis.

White Matter Functional Dysregulation in Amyotrophic Lateral Sclerosis: Machine Learning-Based Biomarkers and Transcriptomic Signatures.

Combined bidirectional spinal cord stimulation for refractory neuropathic pelvic pain: a case report.

Neurovascular unit uncoupling in diabetic retinopathy: molecular mechanisms and stage-adapted therapeutic strategies.

Late-onset ornithine transcarbamylase deficiency with neurological damage and serial brain multimodality monitoring: a case report.

The influence of magnesium ions on the electrophysiological, analgesic, and BDNF-induced neuromodulation of morphine effects in diabetic rats.

Risk factors of nasogastric tube removal failure in acute ischemic stroke patients: a 3-months follow-up cohort study at a single institute.

Related Experiment Videos

From worm genetic networks to complex human diseases

Related Concept Videos

Related Articles