[Erythrocytic membrane permeability in tonsillar pathology]

Area of Science:

• Biophysics
• Hematology
• Colloid Chemistry

Background:

• Erythrocytic membrane permeability is crucial for cell function.
• Quinsy (tonsillitis) can affect red blood cell properties.
• Understanding age-related differences in erythrocyte response is important.

Purpose of the Study:

• To investigate erythrocytic membrane permeability in patients with quinsy using the spectrum method.
• To compare physical and chemical parameters of erythrocytes between different age groups before, during, and after treatment.
• To assess the reliability of the spectrum method for studying cell permeability.

Main Methods:

• Application of the spectrum method to analyze erythrocytic membrane permeability.
• Examination of 140 patients aged 9-16 and 17-31 years with quinsy.
• Measurement of physical and chemical parameters of erythrocytes, including water content and dry matter concentration.

Main Results:

• Before treatment, erythrocyte changes (increased water, decreased dry matter) were similar in both age groups.
• During and after treatment, older patients (17-31 years) exhibited higher erythrocyte physical-chemical parameters than younger patients (9-16 years).
• The spectrum method, based on colloidal optics theory, proved reliable for assessing cell permeability.

Conclusions:

• Age influences the recovery of erythrocytic membrane properties after quinsy treatment.
• The spectrum method is a valid technique for evaluating cell dispersion suspensions and erythrocyte permeability.
• Further research may explore targeted therapeutic strategies based on age-related erythrocyte responses.