Related Experiment Video
Updated: Aug 6, 2026

Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations
Published on: January 10, 2015
Physicians' counseling of patients when prescribing nicotine replacement therapy
Saul Shiffman1, Stuart G Ferguson, Stephen J Hellebusch
1Pinney Associates, Inc., Pittsburgh, PA 15213, USA. shiffman@pinneyassociates.com
Aims:
Nicotine patches and gum are now available without a prescription in many countries. Some have expressed concern that allowing access to these medications without a prescription may deprive smokers of the instruction and support they would otherwise have received from their physician. We assessed the value of physician involvement in NRT prescription.
Design And Participants:
We analyzed data interviews from 993 subjects who had filled prescriptions for patch (n=669) or gum (n=324) about physician behavior when prescribing patch and gum when these were available only by prescription.
Findings:
82% of smokers actually met with the physician; however, only 67% received some instruction in using the medication; only 50% were told about potential side effects; and substantial fractions were prescribed a dose that differed from that recommended on the usage instructions (patch: 24%; gum: 33%). Participants who received no intervention from their physicians were significantly more likely to be abstinent than those participants who received smoking cessation advice and support, likely because physicians offered help to those who most needed it, biasing the association.
Conclusions:
These findings suggest that physicians did not typically perform the helpful behaviors often expected of them or attributed to them.
Related Concept Videos
Drugs Acting on Autonomic Ganglia: Stimulants
Ganglionic stimulants activate NM nicotinic receptors in autonomic ganglia, falling into two categories: nicotine mimetics [e.g., lobeline, dimethylpiperazine, tetramethylammonium] and muscarinic receptor agonists [e.g., muscarine, methacholine]. The first category's action is rapid and blocked by nicotinic receptor antagonists, while the second category's action is delayed and blocked by atropine-like agents. Nicotine, an alkaloid, affects the heart rate by stimulating sympathetic or...
Acute Coronary Syndrome IV: Interprofessional Care
Chronic Obstructive Pulmonary Disease-V: Management
Smoking Cessation
CNS Depressants: Alcohol and Nicotine
Chronic Obstructive Pulmonary Disease-V: Nursing Management
Assessment
Drug Dependence