Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Bronchial asthma and the beta adrenergic system].

J Charpin, P Gayrard, J Orehek

    Allergologia Et Immunopathologia
    |March 1, 1975
    PubMed
    Summary

    Asthma involves the beta-adrenergic system, which controls bronchodilation. Beta-adrenergic drugs like Salbutamol offer effective asthma relief with minimal cardiac side effects.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [The treatment of respiratory pollen allergies].

    Revue medicale de France·2014
    Same author

    About collective accidental chlorine poisoning.

    Annales de medecine legale, criminologie, police scientifique et toxicologie·2010
    Same author

    [Request presented by Madame Guérin-Lemerdy with a view to obtaining authorization to manufacture allergens prepared specially for an individual in the locales of SARL "Allerbio"].

    Bulletin de l'Academie nationale de medecine·1992
    Same author

    Is intrinsic asthma a hereditary disease?

    Allergy·1991
    Same author

    Value of ELISA using A60 antigen in the diagnosis of active pulmonary tuberculosis.

    The American review of respiratory disease·1990
    Same author

    Comparative evaluation of the antitussive activity of butamirate citrate linctus versus clobutinol syrup.

    Respiration; international review of thoracic diseases·1990

    Area of Science:

    • Pulmonology and Pharmacology
    • Autonomic Nervous System Physiology

    Context:

    • The sympathetic nervous system, via beta-receptors, mediates bronchodilation.
    • Beta-adrenergic blockers, like propranolol, can induce bronchoconstriction.
    • The beta-adrenergic system appears to antagonize vagal bronchoconstriction.

    Purpose:

    • To explore the physiopathology and therapeutic implications of the beta-adrenergic system in bronchial asthma.
    • To analyze the role of beta-adrenergic activity in airway smooth muscle function.
    • To compare the therapeutic efficacy and safety of various bronchodilators.

    Summary:

    • Asthma may involve a spontaneous beta-block or hypersensitivity of bronchial receptors.
    • Beta-adrenergic agonists stimulate adenyl cyclase, increasing cAMP and causing bronchial smooth muscle relaxation.
    • Salbutamol demonstrates potent bronchodilator effects with minimal impact on heart dynamics, making it a preferred choice.

    Impact:

    • Highlights Salbutamol and Terbutaline as preferred sympathomimetics for asthma due to low cardiogenic effects.
    • Suggests cautious interpretation of oral administration results for asthma medications.
    • Provides insights into the complex interplay between the autonomic nervous system and asthma management.

    Related Experiment Videos