Related Experiment Video
Updated: Aug 6, 2026

Point-of-Care Kidney and Genitourinary Ultrasound in Adults: Image Acquisition
Published on: June 21, 2024
Factors associated with renal cortical echogenicity
1Finnish Institute of Occupational Health, Helsinki, Finland. tapio.vehmas@ttl.fi
Abstract:
We studied the causes of renal cortical echogenicity (RCE). Its bilateral average value (AvRCE) and the left renal cortex/spleen echo ratios (RCSplE) were determined among 22 workers exposed to industrial solvents and 19 controls. Men had a higher AvRCE than women (p = 0.006). Current exposure to solvents increased AvRCE (p = 0.024), as did any exposure to aliphatic solvents (p < 0.001). AvRCE had a significant negative correlation with liver transaminases AST, ALT and GGT and with serum triglycerides. RCSplE correlated positively with AST, ALT and GGT, with total serum cholesterol and with diastolic blood pressure. Besides renal structural changes, RCE may be influenced by renal flow effects and the presence of macromolecules in renal vessels and tubular systems. Incidentally-found altered RCE may warrant the workout of occupational exposure history and general medical investigation if no kidney disease is known to exist.
Related Concept Videos
Factors Affecting Renal Clearance: Renal Impairment
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
Imaging Studies II: Ultrasonography
Factors Affecting Renal Clearance: Drug's Physicochemical Properties and Plasma Levels
One important factor is the drug's molecular size. The kidneys readily excrete smaller molecules below 300 Daltons (Da). On the other hand, molecules weighing between 300 and 500 Da are excreted through both urine and bile. Larger molecules above 500 Da tend to be excreted less...
Imaging Studies VII: Vascular Imaging
Acute Kidney Injury II: Pathophysiology
Urinary Tract Calculi I: Introduction

