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Updated: Aug 6, 2026

Identification of Virulence Markers of Mycobacterium abscessus for Intracellular Replication in Phagocytes
Published on: September 27, 2018
[Anthrax revisited: Bacillus anthracis toxins as novel actors of immune escape?]
Jean-Nicolas Tournier1, Anne Quesnel-Hellmann, Aurélie Cleret
1Département de Biologie des agents transmissibles, CRSSA, 38702 La Tronche cedex-France.
Abstract:
The recent bioterrorist attacks have stressed the need of a better knowledge of Bacillus anthracis infection pathophysiology. We present here the increasing interests of B. anthracis studies in term of bio-defense, the main pathogen characteristics, the main clinical features of inhalational anthrax (the pulmonary form of the disease), and recent aspects of its physiopathology. Next, we address the main results concerning the toxin effects on immune system through impairing the dendritic cell functions, and we analyze the singular role of anthrax toxins in immune evasion.
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