[Evaluation of the antihypoxic activity of glycine and its phosphorylated derivative]

The antihypoxant activity of glycine and its phosphorilated derivative AKF 90-7 in doses 1, 20, 50 and 100 mg/kg was studied. AKF 90-7 increases the survival of laboratory animals under the conditions of various hypoxia types. The antihypoxic effect of glycine was the same with the effect of AKF 90-7 in hystotoxic hypoxia, but absent on the model of hemic hypoxia and substantially lower than that of AKF 90-7 on the models of hypercapnic and hypobaric hypoxia.