Related Experiment Video
Updated: Aug 6, 2026

Synovial Fluid Analysis to Identify Osteoarthritis
Published on: October 20, 2022
Osteoarticular manifestations of antiphospholipid syndrome
Maria G Tektonidou1, Haralampos M Moutsopoulos
1Department of Pathophysiology, Medical School, National University of Athens, 75 Mikras Asias str, Athens 11527, Greece. balts@otenet.gr
Abstract:
In conclusion, arthralgias represent a rather common osteoarticular manifestation of primary and secondary APS, while arthritis is mainly described in SLE-related APS. Osteonecrosis is frequently described in association with aPL in patients with and without autoimmune disorders. The presence of osteonecrosis in primary APS patients in the absence of corticosteroid use suggests an association between osteonecrosis and APS. Clinicians should be aware of this possible clinical manifestation of APS, because early diagnosis may lead to early management. A systematic screening for aPL in all cases with diagnosed osteonecrosis in the absence of precipitating factors should be considered.
Related Concept Videos
Endocarditis II: Clinical Features of Infective Endocarditis
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Chronic Kidney Disease II: Clinical Manifestations
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests
Peripheral Artery Disease I: Introduction

