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Cytotoxic arylnaphthalene lignans from Phyllanthus oligospermus
1Department of Medical Technology, Chung Hwa College of Medical Technology, Tainan Hsien 717, Taiwan. shwu01054@yahoo.com.tw
Chemical & Pharmaceutical Bulletin
|August 2, 2006
Abstract:
Three new arylnaphthalene lignans, namely phyllanthusmins A-C, together with nine known compounds were isolated and characterized from the stems and roots of Phyllanthus oligospermus by a bioassay-guided purification. The structures of the new compounds were elucidated by means of spectroscopic data interpretation. Among them, phyllanthusminA displayed significant cytotoxicity against KB and P-388 cancer cell lines.